Generally, when making money, you use large positions in mainstream cryptocurrencies like BTC and ETH during periods of high trading volume. A necessary condition for making big profits and rolling over positions is increased trading volume, increased volatility, and sustained volatility. You can't use large positions if any of these three conditions are missing. It's easier to profit from murky waters.
When trading volume is low, you can only profit from those who are willing to take losses. For example, those who like to short altcoins, or those who use leverage to increase their positions when volatility decreases in an attempt to achieve the same profits (as seen in stop-loss/take-loss charts). In this situation, you can only reduce your risk exposure and stay calm; otherwise, you'll become one of those people taking losses...